UpWellness Ultra Liver was born from two decades of clinical practice, thousands of patient conversations, and one naturopathic physician's frustration that most liver supplements on the market simply weren't designed with real liver physiology in mind.
Dr. Joshua Levitt, ND is a licensed naturopathic physician based in Connecticut, USA, with more than 20 years of active clinical practice in integrative and naturopathic medicine. He holds a Doctor of Naturopathic Medicine degree and has built his career around one central belief: that the body has an extraordinary capacity for healing when given the right tools — and that those tools are far more often found in nature than in a pharmacy.
Over two decades of seeing patients with fatigue, weight struggles, digestive complaints, and elevated liver enzymes, Dr. Levitt observed a pattern that conventional medicine consistently overlooked: the liver was almost always involved. Not in a dramatic, disease-level way — but in a quiet, subclinical way that drained energy, impaired fat digestion, and slowly compounded metabolic dysfunction over years.
His clinical response was to develop what would become Ultra Liver — a formula built on the principle that the liver and gallbladder must be supported together, through multiple biological pathways simultaneously, using ingredients with the strongest evidence base in hepatic medicine.
"I designed Ultra Liver to provide a science-backed way to support liver and gallbladder health without ineffective trends like liver flushes or aggressive detox protocols that have no clinical foundation." — Dr. Joshua Levitt, ND
After years of clinical practice, Dr. Levitt identified a pattern he called "Sticky Bile Syndrome" — his term for the way thick, sluggish bile quietly disrupts fat digestion, contributes to fatigue, and impairs the liver's natural detoxification processes. While not a formal clinical diagnosis, the underlying physiology is well-documented: bile viscosity directly affects fat emulsification, cholesterol elimination, and fat-soluble toxin excretion.
The existing solutions frustrated him. Most liver supplements on the market fell into one of three unsatisfying categories: single-ingredient products (usually just milk thistle at doses far below clinical evidence); aggressive detox cleanses with no mechanistic rationale and uncomfortable side effects; or marketing-driven blends with 15+ ingredients at doses too small to be meaningful for any of them.
His clinical answer was different: 10 carefully selected ingredients at meaningful doses, each targeting a specific aspect of liver-gallbladder function, working as a coordinated system rather than a collection of random botanicals.
Each ingredient was selected based on published clinical and preclinical evidence, not marketing appeal. The formula represents Dr. Levitt's clinical distillation of what actually moves the needle for patients struggling with liver-related fatigue, digestive dysfunction, and metabolic imbalance.
UpWellness, LLC is a naturopathic health and wellness company co-founded by Dr. Joshua Levitt, ND, Dr. Amanda Levitt, ND, and Jake Carney. The company was built on the conviction that natural medicine, when practiced with clinical rigor and scientific honesty, can meaningfully improve the health of millions of people who would never visit a naturopathic clinic.
Dr. Amanda Levitt, ND — Dr. Joshua's wife and co-founder — brings her own naturopathic medical degree and clinical perspective to the company's product development and health education mission. Together, the Levitts have built UpWellness into a trusted health brand consumed by hundreds of thousands of readers and customers across the United States.
The UpWellness mission is simple: make the most effective, evidence-grounded natural health solutions accessible to everyday people — not just those who can afford concierge naturopathic care. Ultra Liver is the direct product of that mission applied to the area where Dr. Levitt's clinical experience identified the greatest unmet need: liver and gallbladder health.
"UpWellness exists because real naturopathic medicine should not be a luxury. Every product we create is something I would recommend to my own patients." — Dr. Joshua Levitt, ND
Every ingredient in every UpWellness product is selected based on published clinical or preclinical research. Dr. Levitt does not formulate for marketing appeal — he formulates for biological mechanism. If the evidence is weak or inconsistent, the ingredient doesn't make the formula, regardless of how popular it is in the supplement market.
The naturopathic philosophy at UpWellness rejects the false choice between "natural" and "effective." Berberine compares to metformin in clinical trials. NAC is a hospital-grade hepatoprotective agent. Milk thistle has thousands of published studies. Nature's most powerful compounds simply haven't been patented — which doesn't make them less real.
UpWellness believes customers deserve honest information — including what the evidence does and does not support. That is why this website acknowledges dose transparency limitations, individual variation in results, the difference between ingredient-level and product-level evidence, and drug interactions that require physician oversight. Trust is built on honesty, not hype.
Early in Dr. Levitt's naturopathic practice in Connecticut, a recurring pattern appears across patients presenting with fatigue, stubborn weight gain, and digestive complaints: standard bloodwork looks "normal" or borderline, but liver function is quietly impaired. Conventional medicine has no treatment for subclinical hepatic dysfunction. Dr. Levitt begins developing individualized liver support protocols using botanical and nutritional compounds.
Over hundreds of patient cases, Dr. Levitt identifies bile viscosity as a central but overlooked variable in metabolic and digestive health. Thick, sluggish bile impairs fat digestion, reduces fat-soluble toxin elimination, and contributes to the energy and weight complaints his patients describe. He coins the term "Sticky Bile Syndrome" to communicate this mechanism to patients in accessible terms, and begins refining the ingredient protocol that would become Ultra Liver.
Dr. Joshua Levitt co-founds UpWellness, LLC with Dr. Amanda Levitt and Jake Carney, with the explicit mission of making clinical-grade naturopathic health solutions accessible to the general public. The company begins publishing evidence-based health education content that reaches hundreds of thousands of readers, building a community of people seeking science-grounded natural health information.
After years of clinical refinement, UpWellness Ultra Liver is launched with the 10-ingredient formula Dr. Levitt developed from his clinical experience. The supplement is manufactured in FDA-registered, GMP-certified facilities in the United States and is immediately listed on Amazon and the UpWellness official site. Initial customer response confirms the pattern Dr. Levitt observed clinically: energy, digestion, and metabolic improvements are the most commonly reported early benefits.
Ultra Liver accumulates over 2,800 verified purchases and a 4.6/5 average rating across platforms. Customers report improvements in energy (91%), digestion (74%), and liver bloodwork (61% of those tracking). Post-gallbladder surgery users emerge as one of the most satisfied subgroups, validating the bile-support design rationale. UpWellness continues refining its health education content and expanding access to the formula across the United States.
Every ingredient in Ultra Liver has published research supporting its inclusion. We cite specific journals, explain biological mechanisms, and acknowledge the limits of the evidence — including the distinction between ingredient-level and product-level clinical data. We will never ask you to trust marketing language over science.
Ultra Liver is not formulated by a marketing team who then found a scientist to approve it. It was formulated by a practicing naturopathic physician from clinical experience, then made available to the public. Dr. Levitt would recommend this formula to his own patients — and does.
We acknowledge that no published clinical trial has tested the finished Ultra Liver formula as a complete product. We acknowledge dose transparency limitations. We acknowledge that individual results vary. This honesty is not a weakness — it is the foundation of the trust our customers place in us.
Ultra Liver is manufactured in FDA-registered, GMP-certified facilities in the United States. We maintain full supply chain oversight and quality control at every stage of production. American manufacturing means accountability, traceability, and standards that many imported supplement products do not meet.
The 60-day money-back guarantee is not a marketing device — it is a clinical confidence statement. Dr. Levitt is confident enough in the formula's ability to produce results within two months that he is willing to refund purchases that don't. That confidence is backed by two decades of watching these ingredients work in patients.
We take drug interactions and safety considerations seriously — which is why we disclose berberine's interactions with blood sugar medications, NAC's effects on blood clotting, and milk thistle's cytochrome P450 implications on every relevant page. Responsible natural medicine means honest safety communication, not marketing minimization of risks.
Every bottle of UpWellness Ultra Liver is produced under the highest quality standards available to the US dietary supplement industry. Here is what that means in practice.
Manufactured in facilities registered with the U.S. Food and Drug Administration, meeting all applicable federal manufacturing regulations.
Good Manufacturing Practice (GMP) certification ensures consistent product quality, accurate labeling, and rigorous contamination controls at every production step.
All 10 ingredients are naturally derived. Ultra Liver contains no synthetic additives, artificial colors, or harsh chemical compounds.
Formulated, manufactured, and quality-tested entirely in the United States under the oversight of Dr. Joshua Levitt's formulation standards.
"After three weeks on Ultra Liver, my bloating is gone and my energy levels are through the roof. I feel lighter and more focused every single day. Best decision I made for my health this year!"
Elaine Wood
Wyoming, USA
"My doctor flagged elevated liver enzymes during my checkup. After taking Ultra Liver for three months, my blood work looks great. I also dropped weight without changing my diet drastically. Highly recommend!"
Shawn Mitchell
New York, USA
"I had my gallbladder removed and struggled with digestion for months. Ultra Liver has been gentle yet effective. No harsh side effects — just steady improvements in my digestion and overall well-being. I'm a fan!"
Cassie Smith
Texas, USA
This Special Discount and Free Shipping & Handling Are Only Available for a Limited Time
UpWellness provides a 60-day money-back guarantee on every Ultra Liver purchase made through the official website. This is Dr. Levitt's clinical confidence expressed as a financial commitment: he is confident enough in the formula's effectiveness within a two-month window that he is willing to refund the full product cost if you are not satisfied.
Refunds cover the full product cost less shipping and handling. To initiate a return, contact UpWellness customer service at (800) 876-2196, Monday–Friday 9 AM–9 PM ET or Saturday 9 AM–6 PM ET, or reach them by email through the official website. Returns are sent to the UpWellness Returns address in Buford, Georgia.
The guarantee applies to official website purchases. Amazon and third-party retailer purchases are subject to those platforms' own return policies. For the most comprehensive refund protection, purchase directly through the official UpWellness website.
Regular Price: $99/per bottle
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